Gene absence makes the kid grow rounder

 作者:颛孙谦     |      日期:2019-03-08 03:13:07
“HOLES” in the genomes of severely overweight children have revealed a new type of genetic variant that drives obesity. Such a variant has long been sought. Previous studies in identical twins that were raised apart revealed that genes play a major role in who becomes obese. Pinpointing the culprits has been hard, however: the single-letter genetic variations found to be more common in obese people can only account for a small measure of obesity’s heritability. So geneticists Stephen O’Rahilly and Sadaf Farooqi at the University of Cambridge, and colleagues, turned to a different kind of genetic variation,